Keep in mind
The setting of a study matters when interpreting its findings.
Two terms for different settings
In vitro describes work outside a living body, such as a laboratory experiment. In vivo describes work within a living organism. An in vivo study is not necessarily a study in people.
Where preclinical work fits
Preclinical research can include both settings. It helps researchers investigate questions such as toxicity before deciding whether to proceed to studies in people. Results need to be interpreted within the model and conditions that produced them.
Read the original source
FDA — preclinical research ↗ (opens in a new tab)
NCI — definition of in vitro ↗ (opens in a new tab)
These guides explain research concepts. They do not provide individual medical advice or establish the status of any particular product.